LAMP HUMAN LACTOSE INTOLERANCE KIT
| Format | References |
| 24 reactions | LC-FrucI-LP-24 |
INTENDED USE
The LAMP Human Fructose Intolerance KIT is an in vitro diagnostic KIT for the detection of the main
mutation linked to Hereditary fructose intolerance (rs1800546) by Loop-mediated isothermal
amplification (LAMP). This assay is dedicated to professional use in diagnostic laboratory. The
device is not for self-testing.
DISEASE INFORMATION
Hereditary fructose intolerance is an autosomal recessive disorder, caused by a deficiency in the activity
of aldolase B, a major actor in the metabolism pathway of fructose. Multiple mutations have been
described, of which the A149P polymorphism ( rs1800546 ) is linked to 65% of hereditary fructose
intolerance. Clinical symptoms include vomiting, abdominal pain and diarrhea. Often patients show a food
aversion to fructose rich foods. A strict diet avoiding fructose containing foods is recommended.