Sickle Cell (S&C)

Detection of human Hemoglobin S&C mutation by Loop-mediated isothermal amplification



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Kit CE


The LAMP Human Hemoglobin S&C mutation KIT is an in vitro diagnostic KIT for the detection of the haemoglobin S and C mutations by Loop-mediated isothermal amplification (LAMP). This CE-IVD assay is dedicated to professional use in diagnostic laboratory. The device is not for self-testing.


Sickle cell disorders encompass a wide range of genetic anomalies, including not only sickle cell anemia (homozygous HbSS), but also combination of HbS with other β-globin variants. Sickle cell disorders are clinically marked by the polymerization of HbS in red blood cells, leading to anemia, and acute and chronic tissue damage secondary to blood vessel occlusions. Hb disorders represent the most common single gene disorders in the world, with very high prevalence in some tropical and sub-tropical regions.

Reference :

- Detemmerman, L., Olivier, S., Bours, V., & Boemer, F. (2017). Innovative PCR without DNA extraction for African sickle cell disease diagnosis. Hematology, 23(3), 181–186. Available from : Hematology


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