Pharmacogenetics : revolutionize your diagnostics with personalized medicine
Streamline your workflow with Pharmacogenetics no extraction
Pharmacogenetics no extraction enables direct testing from EDTA whole blood, no DNA extraction needed. Using LAMP-based assays, labs can rapidly detect key TPMT and NUDT15 variants with fewer steps, faster turnaround, and higher efficiency.
This approach simplifies workflows, reduces pre-analytical time, and delivers reliable results to support safer, personalized thiopurine therapies in routine diagnostics.
A three-fold perspective for more targeted treatments
Pharmacogenetic testing provides a comprehensive analysis of an individual’s genetic profile through three key angles:
- Drug metabolism rate : The test reveals how quickly or slowly a patient metabolizes a drug, allowing for accurate, personalized dose adjustments.
- Medication efficacy : It identifies which drugs are likely to be more or less effective based on a patient's genetic makeup.
- Risk of adverse effects : It detects genetic predispositions to side effects, helping to prevent the prescription of potentially harmful medications.
This global approach enables safer, more effective patient care based on objective and individualized data.
Genetic deficiencies targeted by our tests
Certain enzyme deficiencies of genetic origin can cause severe adverse reactions to specific treatments. Our solutions enable laboratories to reliably detect key at-risk genetic profiles, including :
- TPMT : Thiopurine methyltransferase deficiency, critical for the use of thiopurines. TPMT genotyping can be complemented by NUDT15 allele analysis.
- DPD (DPYD) : Important for patients treated with fluoropyrimidines such as fluorouracil or capecitabine.
- CYP2C9 & CYP2C19 : Two major enzymes involved in the metabolism of a wide range of medications, including anticoagulants, anti-inflammatories, and antidepressants.
- NUDT15 : A genetic variant particularly common in certain populations, significantly increasing the risk of thiopurine toxicity.The genotyping of NUDT15 is therefore complementary to the identification of the TPMT risk allele.
Empower your lab with Pharmacogenetics
Our pharmacogenetic solutions for laboratories
At LaCAR MDx Technologies, we design and develop solutions specifically tailored to the needs of molecular genetics laboratories :
- LAMP Kits without DNA extraction
Our kits use Loop-Mediated Isothermal Amplification (LAMP) technology, enabling fast and reliable detection of genetic variations without the need for DNA extraction. This simplifies workflows and significantly reduces turnaround times.
- Customized technical support
We provide hands-on assistance to integrate our kits into your existing laboratory workflows, ensuring a seamless and efficient implementation.
- Dedicated customer support
Our product specialists work closely with your teams to guarantee optimal use and long-term performance of our solutions in your laboratory.
Conclusion: elevate your diagnostic services
Pharmacogenetics is the future of precision diagnostics. With simple, fast, and robust tools, laboratories can become key drivers of personalized medicine.
Embrace pharmacogenetics today with LaCAR MDx Technologies. Together, let’s transform global health.