Autoimmune Diseases
HLA-B27 is strongly associated with the spondyloarthropathies, notably ankylosing spondylitis. Typing supports the diagnostic work-up in patients with suggestive symptoms.
The assays below determine HLA-B27 status under CE-IVD.
The LAMP Human HLA-B27 detection kit is an in vitro diagnostic test intended for the qualitative detection of a tag SNP (rs4349859) for HLAB27 alleles by Loop-mediated isothermal amplification (LAMP) on EDTA whole blood.
The LAMP Human HLA-B27 Direct KIT is an in vitro diagnostic test intended for the qualitative detection of a tag SNP (rs4349859) for HLAB27 alleles by Loop-mediated isothermal amplification (LAMP) on EDTA whole blood and extracted DNA.
Genetic Thrombosis
Inherited thrombophilia is associated with an increased risk of venous thromboembolism. Genotyping supports risk assessment in recurrent thrombosis, family history, or before pregnancy, hormonal contraception or surgery.
LaCAR provides CE-IVD kits for these markers, run from the primary sample.
LaCAR provides CE-IVD kits for these markers, run from the primary sample.
Food Intolerance
Genotyping identifies the genetic basis of primary lactose intolerance (lactase non-persistence) and the HLA-DQ2/DQ8 haplotypes associated with coeliac disease.
LaCAR provides CE-IVD kits for these markers, run from the primary sample.
LaCAR provides CE-IVD kits for these markers, run from the primary sample.
Others
Additional inherited conditions where genotyping informs clinical management, including hereditary hemochromatosis (HFE) and alpha-1 antitrypsin deficiency (SERPINA1).
LaCAR provides CE-IVD kits for SNP detection in these conditions.
LaCAR provides CE-IVD kits for SNP detection in these conditions.
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