DPDrs11
The LAMP Human DPDrs11 KIT is an in vitro diagnostic test intended for the qualitative detection of the less functional DPYD allele c.557A>G (rs115232898) by Loop-mediated isothermal amplification (LAMP) on EDTA whole blood and extracted DNA. This assay is dedicated to professional use in diagnostic laboratories. The device is not for self-testing.
In addition to the four variants of primary relevance, some guidelines suggest the detection of c.557A>G (rs115232898, p.Y186C), as this decreased function variant is relatively common in individuals with African ancestry (3-5% carrier frequency) [1].
[1] https://files.cpicpgx.org/data/guideline/publication/fluoropyrimidines/2017/29152729.pdf
Format: 24 determinations
Storage: At -20°C. 8 freeze and thaw max.
Possible automation: Yes
Analysis software : Yes
Turn around time: Around 1 hour
Test principle
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