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DPDrs11

The LAMP Human DPDrs11 KIT is an in vitro diagnostic test intended for the qualitative detection of the less functional DPYD allele c.557A>G (rs115232898) by Loop-mediated isothermal amplification (LAMP) on EDTA whole blood and extracted DNA. This assay is dedicated to professional use in diagnostic laboratories. The device is not for self-testing.

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In addition to the four variants of primary relevance, some guidelines suggest the detection of c.557A>G (rs115232898, p.Y186C), as this decreased function variant is relatively common in individuals with African ancestry (3-5% carrier frequency) [1].

[1] https://files.cpicpgx.org/data/guideline/publication/fluoropyrimidines/2017/29152729.pdf

General information

Format: 24 determinations
Storage: At -20°C. 8 freeze and thaw max.
Possible automation: Yes
Analysis software : Yes
Turn around time: Around 1 hour

Test principle

Advantages

icon fast
Fast
icon No-DNA-extraction
No DNA extraction
icon comprehensive
Compatible with a variety of qPCR machines
icon easy-to-use
Automatic interpretation of the results

Linked products

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DPD4mut
The LAMP Human DPD deficiency KIT is an in vitro diagnostic test intended for the qualitative detection of four different non-functional or less functional DPYD alleles by Loop-mediated isothermal amplification (LAMP) on EDTA whole blood and extracted DNA.
LaCar
DPD4var
The LAMP Human DPD4var KIT is an in vitro diagnostic test intended for the qualitative detection of four different non-functional or less functional DPYD alleles by Loop-mediated isothermal amplification (LAMP) on EDTA whole blood and extracted DNA.

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